Hi dajo,
site url is: www.domenica-aperto.it/
you can click an item on "Ultime attività inserite" (Last item) and you can see a different layout (without modules)

For example this: www.domenica-aperto.it/index.php/component/k2/item/5221-crai
Or this: www.domenica-aperto.it/index.php?option=...tem&id=5221:crai

But if I turn on ARTIO the link is: www.domenica-aperto.it/home/negozi/alimentari/crai and open the wrong item in a wrong layout (with the home modules)

Thanks again for your help

And what are the Real non-SEF URL and Itemid for "home/negozi/alimentari/crai" SEF URL stored in JoomSEF's URLs Manager?

For 4 items the same SEF URL:

home/negozi/alimentari/crai -> index.php?option=com_k2&id=5221&view=item&Itemid=1
home/negozi/alimentari/crai -> index.php?option=com_k2&id=5220&view=item&Itemid=1
home/negozi/alimentari/crai -> index.php?option=com_k2&id=5219&view=item&Itemid=1
home/negozi/alimentari/crai -> index.php?option=com_k2&id=5218&view=item&Itemid=1

Thanks

Open JoomSEF -> Manage Extensions -> K2 -> Common tab and try setting the "Itemid handling" to "Override" and leave "Override Itemid" field empty.

I've the same problem, no right itemid!

I've just tested it and I can confirm this problem. We'll fix it in next version of JoomSEF.